In the Setetori region of the southern part of the Raulbhach continent lies the Mikelti Kingdom, and amongst the seven major cities of this region is the workshop city of Yuidora. This is where a young orphan named Wilfred lives, pursuing his dream of becoming an alchemist. However, soon after gaining his license he gets entangled with three girls with differing personalities and goals, and he soon agrees to hire them as his guards in order to help each other out. Like this, Wil begins his life as an alchemist, surrounded by the ever growing group of his allies as he follows his parents' footsteps in becoming a great alchemist.
The game features 3 routes, one for each main heroine. The route you take changes which of the three you romance as well as unlocking specific quests.
At some point during chapter 3 ( sometime it will happen at chapter 2 ) you will be awoken at night and can either go hit on Yuela or go back to sleep. If you hit on her you will be locked into Yuela's route.
Regardless of your choice, you will later be asked by Serawi to come with her to see something really important, but you already had plans with the other two girls. If you choose "Serawi is more important" and go with her you will start the Serawi route, but only if you did not already start Yuela's route; if you did start Yuela's route you will go with Serawi and learn about corruption, but will go no further with her, remaining in the Yuela Route.
If you chose to turn down both Yuela and Serawi, you will automatically be pushed into the Emilita route.